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Creatine is a compound, produced primarily by the liver. It is an energy source that is utilized for muscle contracts. Creatinine is a waste product of creatine, which is produced by the muscles and removed from the body by the kidneys.
As almost all creatinine is filtered from the blood by the kidneys, its blood levels are usually a good indicator of kidney functions. Its level depends on the muscle mass, therefore its levels are slightly higher in men than in women.
The test helps to assess the normal function of the kidneys and to monitor the treatment of kidney disease. Usually, the test will be requested by the doctor along with a carbamide test if the patient has a kidney disorder.
The test measures the levels of creatinine in the blood and/or urine.

The test is usually performed as part of a metabolism test, or if the doctor suspects renal failure, or in case of an acute or chronic disease that may cause renal dysfunction.
The test is often used to check kidney function besides medication or to control the effectiveness of certain medicines.
A blood sample, taken from a vein, and/or a 24-hour urine sample are needed for the test.
Increased creatinine levels
If your blood creatinine level is elevated, it may indicate the presence of the following conditions / diseases:
Low creatinine levels
Decreased creatinine levels can be caused by a decrease in muscle mass or may occur mildly during pregnancy.
In all cases, please consult the specialist who ordered the test, as the results of further tests may be required for an accurate diagnosis.
Informational content only The textual content published on this page is for general information purposes only and does not constitute medical advice, a diagnosis, or a treatment recommendation. Proper assessment, examination, and therapeutic decisions always require a personal medical consultation and, where appropriate, further specialist opinion. Medicare Egészségközpont Zrt. makes every reasonable effort to keep the content up to date; however, it accepts no liability for the completeness or accuracy of the information published or for consequences arising from decisions based on it.