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GOT (glutamic oxaloacetic transaminase) or AST (aspartate aminotransferase)

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Közzétéve: 2022. 02. 09. Kb. 2 perc olvasási idő Medicare

It is an enzyme involved in the metabolism of amino acids. It occurs mainly in the liver and heart but is also found in the brain and kidneys. It is tested together with the enzyme GPT to evaluate the pathological process. It is normally present in small amounts in the blood, but in the case of organ damage, this level increases significantly.

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What does the test show?

The test is used to show the extent of liver damage.

In which cases is it recommended to perform the test?

Your doctor may order the test as part of a routine laboratory test along with other items of liver function and if they think you have symptoms of liver damage. Such symptoms may include:

  • jaundice
  • constant feeling of tiredness
  • loss of appetite or indigestion
  • changes in the colour of urine and faeces

What sample is needed for the test?

A blood sample taken from a vein is needed for the test.

What can the result indicate?

The following liver-related causes may be behind the increase in GOT levels:

  • Malignant tumour of the liver
  • Inhalation of toxic substances (e.g. organic solvents)
  • Viral hepatitis
  • Chronic hepatocyte damage
  • Consequences of taking certain medicines (e.g. cholesterol-lowering, contraceptive pill)
  • Gallstones

What to do after the test?

The test alone cannot diagnose any disease, and in all cases consult an internist or haematologist to determine the exact diagnosis and required therapy.

Informational content only The textual content published on this page is for general information purposes only and does not constitute medical advice, a diagnosis, or a treatment recommendation. Proper assessment, examination, and therapeutic decisions always require a personal medical consultation and, where appropriate, further specialist opinion. Medicare Egészségközpont Zrt. makes every reasonable effort to keep the content up to date; however, it accepts no liability for the completeness or accuracy of the information published or for consequences arising from decisions based on it.