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Thyreoidea-peroxidáz autoantitest (anti-TPO)
Anti-thyroid peroxidase antibodies (anti-TPO)
Thyroid peroxidase (TPO) is an enzyme that plays an important role in the synthesis of thyroid hormones (thyroxine – T4 and triiodothyronine – T3). An autoantibody produced against it (anti-TPO) can interfere with the synthesis of hormones (T4 and T3), but in many cases it is asymptomatic. Its importance is in the diagnosis of autoimmune thyroid disease.
What does the test show?
The laboratory test detects the amount of anti-thyroid peroxidase autoantibody in the blood.
When is it recommended to have the test?
Anti-TPO testing is recommended in all cases where TSH, T4 and T3 levels are abnormal. The result of the test can help to determine the cause of the thyroid dysfunction and to design the appropriate medication.
Determination of anti-TPO levels may also be necessary in pregnancy, especially when there is a diagnosis of autoimmune disease (e.g. Hashimoto’s or Graves-Basedow disease).
What sample is needed for the test?
The test requires a blood sample taken from a vein.
What can the result indicate?
A high anti-TPO level means that the body is producing antibodies against the important thyroid enzyme TPO. This is an autoimmune process and with appropriate medication, a symptom-free condition can be achieved.
What to do after the test?
The test alone does not diagnose any disease, and you should always consult an endocrinologist with the results to determine the exact diagnosis and the necessary therapy.
Informational content only The textual content published on this page is for general information purposes only and does not constitute medical advice, a diagnosis, or a treatment recommendation. Proper assessment, examination, and therapeutic decisions always require a personal medical consultation and, where appropriate, further specialist opinion. Medicare Egészségközpont Zrt. makes every reasonable effort to keep the content up to date; however, it accepts no liability for the completeness or accuracy of the information published or for consequences arising from decisions based on it.